Transcriptome sequence and plasmid copy number analysis of the brewery isolate Pediococcus claussenii ATCC BAA-344 T during growth in beer.

Growth of specific lactic acid bacteria in beer leads to spoiled product and economic loss for the brewing industry.Microbial growth is typically inhibited by the combined stresses found in beer (e.g., ethanol, hops, low pH, minimal nutrients); however, certain bacteria have adapted to grow in this harsh environment.Considering little is known abou

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Differential effects of desvenlafaxine on hot flashes in women with breast cancer taking tamoxifen: a randomized controlled trial

Abstract Hot flashes (HF) are a common adverse event of prolonged tamoxifen use in women with estrogen receptor-positive breast cancer, impacting psychiatric health and quality of life.While desvenlafaxine does not interact with tamoxifen, its efficacy and safety in breast cancer patients remain unstudied.This phase 3, four-week, multi-center, thre

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